Construction and analysis of a database for medication errors in a pharmacovigilance centre-the Moroccan experience.
Identifieur interne : 000060 ( Main/Exploration ); précédent : 000059; suivant : 000061Construction and analysis of a database for medication errors in a pharmacovigilance centre-the Moroccan experience.
Auteurs : Loubna Alj [Maroc] ; Raja Benkirane [Maroc] ; Amina Tebaa [Maroc] ; Ghita Benabdallah [Maroc] ; Alem Zekaria [Suède] ; Asmae Khattabi [Maroc] ; Rachida Soulaymani Bencheikh [Maroc]Source :
- European journal of clinical pharmacology [ 1432-1041 ] ; 2021.
Abstract
PURPOSE
The study aimed to describe the epidemiological profile of medication errors (MEs) reported to the Moroccan Pharmacovigilance Center (MPVC), to determine factors associated with serious MEs, and to describe signals related to them.
METHODS
We carried out a retrospective descriptive analysis of MEs reported to the MPVC from 2006 to 2016 and a secondary analysis of the seriousness of MEs with adverse drug reactions (ADRs). The reports were sorted by demographic profile and by ME and ADR characteristics. For signal detection, a quantitative approach was adopted, and the root cause analysis was completed. Epi info 7 software was used to perform descriptive and analytical statistics. The statistical significance level was set at p < 0.05.
RESULTS
A total of 1618 ME reports were retrieved. The proportion of MEs associated with serious ADRs was 23.9%. The factors statistically associated with serious MEs were as follows: (i) the age group 16 years old and less (p < 0.001), (ii) the gender (p = 0.01), (iii) the administration and the prescription stages (p < 0.001), and (iv) the ME types related to inappropriate schedule of drug administration, drug prescribing error (p < 0.001), and incorrect drug administration dosage form (p = 0.04). Fourteen signals related to MEs were detected, for which risk minimization actions were implemented.
CONCLUSION
The establishment of a ME unit within the MPVC was an opportunity to further improve the pharmacovigilance centre performance and consequently its contribution to medication safety. The lessons learned from MEs should be shared through pharmacovigilance networks and with institutions involved in medication safety for synergistic results to achieve patient safety worldwide.
DOI: 10.1007/s00228-021-03109-w
PubMed: 33598764
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Construction and analysis of a database for medication errors in a pharmacovigilance centre-the Moroccan experience.</title><author><name sortKey="Alj, Loubna" sort="Alj, Loubna" uniqKey="Alj L" first="Loubna" last="Alj">Loubna Alj</name><affiliation wicri:level="3"><nlm:affiliation>Centre Anti Poison et de Pharmacovigilance du Maroc, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6671, Rabat, Morocco. naloub20@yahoo.fr.</nlm:affiliation><country xml:lang="fr">Maroc</country><wicri:regionArea>Centre Anti Poison et de Pharmacovigilance du Maroc, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6671, Rabat</wicri:regionArea><placeName><settlement type="city">Rabat</settlement><region nuts="2">Rabat-Salé-Kénitra</region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Field Epidemiology Training Program, Ecole Nationale de Santé Publique, Ministry of Health, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6329, Rabat, Morocco. naloub20@yahoo.fr.</nlm:affiliation><country xml:lang="fr">Maroc</country><wicri:regionArea>Field Epidemiology Training Program, Ecole Nationale de Santé Publique, Ministry of Health, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6329, Rabat</wicri:regionArea><placeName><settlement type="city">Rabat</settlement><region nuts="2">Rabat-Salé-Kénitra</region></placeName></affiliation></author><author><name sortKey="Benkirane, Raja" sort="Benkirane, Raja" uniqKey="Benkirane R" first="Raja" last="Benkirane">Raja Benkirane</name><affiliation wicri:level="3"><nlm:affiliation>Ecole Nationale de Santé Publique, Ministry of Health, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6329, Rabat, Morocco.</nlm:affiliation><country xml:lang="fr">Maroc</country><wicri:regionArea>Ecole Nationale de Santé Publique, Ministry of Health, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6329, Rabat</wicri:regionArea><placeName><settlement type="city">Rabat</settlement><region nuts="2">Rabat-Salé-Kénitra</region></placeName></affiliation></author><author><name sortKey="Tebaa, Amina" sort="Tebaa, Amina" uniqKey="Tebaa A" first="Amina" last="Tebaa">Amina Tebaa</name><affiliation wicri:level="3"><nlm:affiliation>Centre Anti Poison et de Pharmacovigilance du Maroc, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6671, Rabat, Morocco.</nlm:affiliation><country xml:lang="fr">Maroc</country><wicri:regionArea>Centre Anti Poison et de Pharmacovigilance du Maroc, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6671, Rabat</wicri:regionArea><placeName><settlement type="city">Rabat</settlement><region nuts="2">Rabat-Salé-Kénitra</region></placeName></affiliation></author><author><name sortKey="Benabdallah, Ghita" sort="Benabdallah, Ghita" uniqKey="Benabdallah G" first="Ghita" last="Benabdallah">Ghita Benabdallah</name><affiliation wicri:level="3"><nlm:affiliation>Centre Anti Poison et de Pharmacovigilance du Maroc, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6671, Rabat, Morocco.</nlm:affiliation><country xml:lang="fr">Maroc</country><wicri:regionArea>Centre Anti Poison et de Pharmacovigilance du Maroc, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6671, Rabat</wicri:regionArea><placeName><settlement type="city">Rabat</settlement><region nuts="2">Rabat-Salé-Kénitra</region></placeName></affiliation></author><author><name sortKey="Zekaria, Alem" sort="Zekaria, Alem" uniqKey="Zekaria A" first="Alem" last="Zekaria">Alem Zekaria</name><affiliation wicri:level="1"><nlm:affiliation>Uppsala Monitoring Center, Bredgränd 7b, 753 20, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Uppsala Monitoring Center, Bredgränd 7b, 753 20, Uppsala</wicri:regionArea><wicri:noRegion>Uppsala</wicri:noRegion></affiliation></author><author><name sortKey="Khattabi, Asmae" sort="Khattabi, Asmae" uniqKey="Khattabi A" first="Asmae" last="Khattabi">Asmae Khattabi</name><affiliation wicri:level="3"><nlm:affiliation>Field Epidemiology Training Program, Ecole Nationale de Santé Publique, Ministry of Health, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6329, Rabat, Morocco.</nlm:affiliation><country xml:lang="fr">Maroc</country><wicri:regionArea>Field Epidemiology Training Program, Ecole Nationale de Santé Publique, Ministry of Health, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6329, Rabat</wicri:regionArea><placeName><settlement type="city">Rabat</settlement><region nuts="2">Rabat-Salé-Kénitra</region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Ecole Nationale de Santé Publique, Ministry of Health, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6329, Rabat, Morocco.</nlm:affiliation><country xml:lang="fr">Maroc</country><wicri:regionArea>Ecole Nationale de Santé Publique, Ministry of Health, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6329, Rabat</wicri:regionArea><placeName><settlement type="city">Rabat</settlement><region nuts="2">Rabat-Salé-Kénitra</region></placeName></affiliation></author><author><name sortKey="Soulaymani Bencheikh, Rachida" sort="Soulaymani Bencheikh, Rachida" uniqKey="Soulaymani Bencheikh R" first="Rachida" last="Soulaymani Bencheikh">Rachida Soulaymani Bencheikh</name><affiliation wicri:level="3"><nlm:affiliation>Centre Anti Poison et de Pharmacovigilance du Maroc, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6671, Rabat, Morocco.</nlm:affiliation><country xml:lang="fr">Maroc</country><wicri:regionArea>Centre Anti Poison et de Pharmacovigilance du Maroc, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6671, Rabat</wicri:regionArea><placeName><settlement type="city">Rabat</settlement><region nuts="2">Rabat-Salé-Kénitra</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2021">2021</date><idno type="RBID">pubmed:33598764</idno><idno type="pmid">33598764</idno><idno type="doi">10.1007/s00228-021-03109-w</idno><idno type="wicri:Area/Main/Corpus">000048</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000048</idno><idno type="wicri:Area/Main/Curation">000048</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000048</idno><idno type="wicri:Area/Main/Exploration">000048</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Construction and analysis of a database for medication errors in a pharmacovigilance centre-the Moroccan experience.</title><author><name sortKey="Alj, Loubna" sort="Alj, Loubna" uniqKey="Alj L" first="Loubna" last="Alj">Loubna Alj</name><affiliation wicri:level="3"><nlm:affiliation>Centre Anti Poison et de Pharmacovigilance du Maroc, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6671, Rabat, Morocco. naloub20@yahoo.fr.</nlm:affiliation><country xml:lang="fr">Maroc</country><wicri:regionArea>Centre Anti Poison et de Pharmacovigilance du Maroc, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6671, Rabat</wicri:regionArea><placeName><settlement type="city">Rabat</settlement><region nuts="2">Rabat-Salé-Kénitra</region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Field Epidemiology Training Program, Ecole Nationale de Santé Publique, Ministry of Health, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6329, Rabat, Morocco. naloub20@yahoo.fr.</nlm:affiliation><country xml:lang="fr">Maroc</country><wicri:regionArea>Field Epidemiology Training Program, Ecole Nationale de Santé Publique, Ministry of Health, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6329, Rabat</wicri:regionArea><placeName><settlement type="city">Rabat</settlement><region nuts="2">Rabat-Salé-Kénitra</region></placeName></affiliation></author><author><name sortKey="Benkirane, Raja" sort="Benkirane, Raja" uniqKey="Benkirane R" first="Raja" last="Benkirane">Raja Benkirane</name><affiliation wicri:level="3"><nlm:affiliation>Ecole Nationale de Santé Publique, Ministry of Health, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6329, Rabat, Morocco.</nlm:affiliation><country xml:lang="fr">Maroc</country><wicri:regionArea>Ecole Nationale de Santé Publique, Ministry of Health, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6329, Rabat</wicri:regionArea><placeName><settlement type="city">Rabat</settlement><region nuts="2">Rabat-Salé-Kénitra</region></placeName></affiliation></author><author><name sortKey="Tebaa, Amina" sort="Tebaa, Amina" uniqKey="Tebaa A" first="Amina" last="Tebaa">Amina Tebaa</name><affiliation wicri:level="3"><nlm:affiliation>Centre Anti Poison et de Pharmacovigilance du Maroc, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6671, Rabat, Morocco.</nlm:affiliation><country xml:lang="fr">Maroc</country><wicri:regionArea>Centre Anti Poison et de Pharmacovigilance du Maroc, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6671, Rabat</wicri:regionArea><placeName><settlement type="city">Rabat</settlement><region nuts="2">Rabat-Salé-Kénitra</region></placeName></affiliation></author><author><name sortKey="Benabdallah, Ghita" sort="Benabdallah, Ghita" uniqKey="Benabdallah G" first="Ghita" last="Benabdallah">Ghita Benabdallah</name><affiliation wicri:level="3"><nlm:affiliation>Centre Anti Poison et de Pharmacovigilance du Maroc, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6671, Rabat, Morocco.</nlm:affiliation><country xml:lang="fr">Maroc</country><wicri:regionArea>Centre Anti Poison et de Pharmacovigilance du Maroc, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6671, Rabat</wicri:regionArea><placeName><settlement type="city">Rabat</settlement><region nuts="2">Rabat-Salé-Kénitra</region></placeName></affiliation></author><author><name sortKey="Zekaria, Alem" sort="Zekaria, Alem" uniqKey="Zekaria A" first="Alem" last="Zekaria">Alem Zekaria</name><affiliation wicri:level="1"><nlm:affiliation>Uppsala Monitoring Center, Bredgränd 7b, 753 20, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Uppsala Monitoring Center, Bredgränd 7b, 753 20, Uppsala</wicri:regionArea><wicri:noRegion>Uppsala</wicri:noRegion></affiliation></author><author><name sortKey="Khattabi, Asmae" sort="Khattabi, Asmae" uniqKey="Khattabi A" first="Asmae" last="Khattabi">Asmae Khattabi</name><affiliation wicri:level="3"><nlm:affiliation>Field Epidemiology Training Program, Ecole Nationale de Santé Publique, Ministry of Health, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6329, Rabat, Morocco.</nlm:affiliation><country xml:lang="fr">Maroc</country><wicri:regionArea>Field Epidemiology Training Program, Ecole Nationale de Santé Publique, Ministry of Health, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6329, Rabat</wicri:regionArea><placeName><settlement type="city">Rabat</settlement><region nuts="2">Rabat-Salé-Kénitra</region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Ecole Nationale de Santé Publique, Ministry of Health, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6329, Rabat, Morocco.</nlm:affiliation><country xml:lang="fr">Maroc</country><wicri:regionArea>Ecole Nationale de Santé Publique, Ministry of Health, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6329, Rabat</wicri:regionArea><placeName><settlement type="city">Rabat</settlement><region nuts="2">Rabat-Salé-Kénitra</region></placeName></affiliation></author><author><name sortKey="Soulaymani Bencheikh, Rachida" sort="Soulaymani Bencheikh, Rachida" uniqKey="Soulaymani Bencheikh R" first="Rachida" last="Soulaymani Bencheikh">Rachida Soulaymani Bencheikh</name><affiliation wicri:level="3"><nlm:affiliation>Centre Anti Poison et de Pharmacovigilance du Maroc, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6671, Rabat, Morocco.</nlm:affiliation><country xml:lang="fr">Maroc</country><wicri:regionArea>Centre Anti Poison et de Pharmacovigilance du Maroc, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6671, Rabat</wicri:regionArea><placeName><settlement type="city">Rabat</settlement><region nuts="2">Rabat-Salé-Kénitra</region></placeName></affiliation></author></analytic><series><title level="j">European journal of clinical pharmacology</title><idno type="eISSN">1432-1041</idno><imprint><date when="2021" type="published">2021</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>PURPOSE</b></p><p>The study aimed to describe the epidemiological profile of medication errors (MEs) reported to the Moroccan Pharmacovigilance Center (MPVC), to determine factors associated with serious MEs, and to describe signals related to them.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>We carried out a retrospective descriptive analysis of MEs reported to the MPVC from 2006 to 2016 and a secondary analysis of the seriousness of MEs with adverse drug reactions (ADRs). The reports were sorted by demographic profile and by ME and ADR characteristics. For signal detection, a quantitative approach was adopted, and the root cause analysis was completed. Epi info 7 software was used to perform descriptive and analytical statistics. The statistical significance level was set at p < 0.05.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>A total of 1618 ME reports were retrieved. The proportion of MEs associated with serious ADRs was 23.9%. The factors statistically associated with serious MEs were as follows: (i) the age group 16 years old and less (p < 0.001), (ii) the gender (p = 0.01), (iii) the administration and the prescription stages (p < 0.001), and (iv) the ME types related to inappropriate schedule of drug administration, drug prescribing error (p < 0.001), and incorrect drug administration dosage form (p = 0.04). Fourteen signals related to MEs were detected, for which risk minimization actions were implemented.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>The establishment of a ME unit within the MPVC was an opportunity to further improve the pharmacovigilance centre performance and consequently its contribution to medication safety. The lessons learned from MEs should be shared through pharmacovigilance networks and with institutions involved in medication safety for synergistic results to achieve patient safety worldwide.</p></div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">33598764</PMID><DateRevised><Year>2021</Year><Month>02</Month><Day>18</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1432-1041</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2021</Year><Month>Feb</Month><Day>17</Day></PubDate></JournalIssue><Title>European journal of clinical pharmacology</Title><ISOAbbreviation>Eur J Clin Pharmacol</ISOAbbreviation></Journal><ArticleTitle>Construction and analysis of a database for medication errors in a pharmacovigilance centre-the Moroccan experience.</ArticleTitle><ELocationID EIdType="doi" ValidYN="Y">10.1007/s00228-021-03109-w</ELocationID><Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">The study aimed to describe the epidemiological profile of medication errors (MEs) reported to the Moroccan Pharmacovigilance Center (MPVC), to determine factors associated with serious MEs, and to describe signals related to them.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">We carried out a retrospective descriptive analysis of MEs reported to the MPVC from 2006 to 2016 and a secondary analysis of the seriousness of MEs with adverse drug reactions (ADRs). The reports were sorted by demographic profile and by ME and ADR characteristics. For signal detection, a quantitative approach was adopted, and the root cause analysis was completed. Epi info 7 software was used to perform descriptive and analytical statistics. The statistical significance level was set at p < 0.05.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">A total of 1618 ME reports were retrieved. The proportion of MEs associated with serious ADRs was 23.9%. The factors statistically associated with serious MEs were as follows: (i) the age group 16 years old and less (p < 0.001), (ii) the gender (p = 0.01), (iii) the administration and the prescription stages (p < 0.001), and (iv) the ME types related to inappropriate schedule of drug administration, drug prescribing error (p < 0.001), and incorrect drug administration dosage form (p = 0.04). Fourteen signals related to MEs were detected, for which risk minimization actions were implemented.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The establishment of a ME unit within the MPVC was an opportunity to further improve the pharmacovigilance centre performance and consequently its contribution to medication safety. The lessons learned from MEs should be shared through pharmacovigilance networks and with institutions involved in medication safety for synergistic results to achieve patient safety worldwide.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Alj</LastName><ForeName>Loubna</ForeName><Initials>L</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-5464-378X</Identifier><AffiliationInfo><Affiliation>Centre Anti Poison et de Pharmacovigilance du Maroc, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6671, Rabat, Morocco. naloub20@yahoo.fr.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Field Epidemiology Training Program, Ecole Nationale de Santé Publique, Ministry of Health, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6329, Rabat, Morocco. naloub20@yahoo.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Benkirane</LastName><ForeName>Raja</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Ecole Nationale de Santé Publique, Ministry of Health, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6329, Rabat, Morocco.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tebaa</LastName><ForeName>Amina</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Centre Anti Poison et de Pharmacovigilance du Maroc, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6671, Rabat, Morocco.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Benabdallah</LastName><ForeName>Ghita</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Centre Anti Poison et de Pharmacovigilance du Maroc, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6671, Rabat, Morocco.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zekaria</LastName><ForeName>Alem</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Uppsala Monitoring Center, Bredgränd 7b, 753 20, Uppsala, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Khattabi</LastName><ForeName>Asmae</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Field Epidemiology Training Program, Ecole Nationale de Santé Publique, Ministry of Health, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6329, Rabat, Morocco.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Ecole Nationale de Santé Publique, Ministry of Health, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6329, Rabat, Morocco.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Soulaymani Bencheikh</LastName><ForeName>Rachida</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Centre Anti Poison et de Pharmacovigilance du Maroc, Rue Lamfadel Cherkaoui, Madinate Al Irfane, BP: 6671, Rabat, Morocco.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2021</Year><Month>02</Month><Day>17</Day></ArticleDate></Article><MedlineJournalInfo><Country>Germany</Country><MedlineTA>Eur J Clin Pharmacol</MedlineTA><NlmUniqueID>1256165</NlmUniqueID><ISSNLinking>0031-6970</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Medication errors</Keyword><Keyword MajorTopicYN="N">Medication safety</Keyword><Keyword MajorTopicYN="N">Pharmacovigilance</Keyword><Keyword MajorTopicYN="N">Risk minimization action</Keyword><Keyword MajorTopicYN="N">Root cause analysis</Keyword><Keyword MajorTopicYN="N">Signal detection</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>07</Month><Day>28</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2021</Year><Month>02</Month><Day>07</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2021</Year><Month>2</Month><Day>18</Day><Hour>6</Hour><Minute>13</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2021</Year><Month>2</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2021</Year><Month>2</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">33598764</ArticleId><ArticleId IdType="doi">10.1007/s00228-021-03109-w</ArticleId><ArticleId IdType="pii">10.1007/s00228-021-03109-w</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>European Medicines Agency. Good practice guide on recording, coding, reporting and assessment of medication errors. https://www.ema.europa.eu/en/documents/regulatory-procedural-guideline/good-practice-guide-recording-coding-reporting-assessment-medication-errors_en.pdf (2015). Accessed 18 June 2020.</Citation></Reference><Reference><Citation>Elliott RA, Camacho E, Campbell F, Jankovic D, Martyn-St James M, Kaltenthaler E and al. Prevalence and economic burden of medication errors in the NHS in England: rapid evidence synthesis and economic analysis of the prevalence and burden of medication error in the UK. Policy Research Unit in Economic Evaluation of Health and Care Interventions (EEPRU), 2018. 174 p. https://pure.york.ac.uk/portal/en/publications/prevalence-and-economic-burden-of-medication-errors-in-the-nhs-in-england(dfaa1403-5ac8-4a35-85c9-b10dd2e8668f)/export.html . Accessed 7 May 2020.</Citation></Reference><Reference><Citation>Kohn LT, Corrigan JM, Donaldson MS (2000) To Err is human: building a safer health system. Institute of Medicine (US) Committee on Quality of Health Care in America National Academy. National Academies Press (US), Washington (DC). https://doi.org/10.17226/9728</Citation><ArticleIdList><ArticleId IdType="doi">10.17226/9728</ArticleId></ArticleIdList></Reference><Reference><Citation>Aitken M, Gorokhovich L (2012) Advancing the responsible use of medicines: applying levers for change. September 17. https://doi.org/10.2139/ssrn.2222541 . Accessed 7 May 2020.</Citation></Reference><Reference><Citation>Walsh EK, Hansen CR, Sahm LJ, Kearney PM, Doherty E, Bradley CP (2017) Economic impact of medication error: a systematic review. Pharmacoepidemiol Drug Saf 26(5):481–497. https://doi.org/10.1002/pds.4188</Citation><ArticleIdList><ArticleId IdType="doi">10.1002/pds.4188</ArticleId><ArticleId IdType="pubmed">28295821</ArticleId></ArticleIdList></Reference><Reference><Citation>Al-lela O, Bahari MB, Al-abassi ME et al (2012) Estimation of immunization providers’ activities cost, medication cost, and immunization dose errors cost in Iraq. Vaccine. 30(26):3862–3866</Citation><ArticleIdList><ArticleId IdType="doi">10.1016/j.vaccine.2012.04.014</ArticleId></ArticleIdList></Reference><Reference><Citation>Ranshaw J, Gupta KJ, Cook TM (2009) Litigation related to drug errors in anesthesia: an analysis of claims against the NHS in England 1995-2007. Anaesthesia. 64(12):1317–1323</Citation><ArticleIdList><ArticleId IdType="doi">10.1111/j.1365-2044.2009.06107.x</ArticleId></ArticleIdList></Reference><Reference><Citation>Soulaymani Bencheikh R, Benabdallah G (2009) Medication errors: pharmacovigilance centres in detection and prevention. Br J Clin Pharmacol 67(6):687–690. https://doi.org/10.1111/j.1365-2125.2009.03426.x</Citation><ArticleIdList><ArticleId IdType="doi">10.1111/j.1365-2125.2009.03426.x</ArticleId></ArticleIdList></Reference><Reference><Citation>Kunac DL, Tatley MV (2011) Detecting medication errors in the New Zealand pharmacovigilance database. Drug Saf 34:59–71. https://doi.org/10.2165/11539290-000000000-00000</Citation><ArticleIdList><ArticleId IdType="doi">10.2165/11539290-000000000-00000</ArticleId><ArticleId IdType="pubmed">21142271</ArticleId></ArticleIdList></Reference><Reference><Citation>Alj L, Touzani MDW, Benkirane R, Edwards IR, Soulaymani R (2007) Detecting medication errors in pharmacovigilance database: capacities and limits. Int J Risk Saf Med 19:187–194</Citation></Reference><Reference><Citation>World Health Organization. Reporting and learning systems for medication errors: the role of pharmacovigilance centres (2014). https://apps.who.int/iris/handle/10665/137036 . Accessed 22 May 2020.</Citation></Reference><Reference><Citation>The Erice Manifesto. Drug-Safety 30, 187–190 (2007). https://doi.org/10.2165/00002018-200730030-0000 .</Citation></Reference><Reference><Citation>Edwards IR (2017 Oct) A new Erice report considering the safety of medicines in the 21st century. Drug Saf 40(10):845–849. https://doi.org/10.1007/s40264-017-0571-9</Citation><ArticleIdList><ArticleId IdType="doi">10.1007/s40264-017-0571-9</ArticleId><ArticleId IdType="pubmed">28815462</ArticleId><ArticleId IdType="pmcid">5606955</ArticleId></ArticleIdList></Reference><Reference><Citation>Improving the detection, analysis, and reporting of harms in medicines and devices – statement from the 2019 4Es Forum. https://www.cebm.net/wpcontent/uploads/2019/12/The-Erice-Statement.pdf . Accessed 22 May 2020.</Citation></Reference><Reference><Citation>Gerard R. Ten critical steps to improve patient safety worldwide. 10 March 2020. https://view.publitas.com/uppsala-monitoring-centre/uppsala-reports-82/page/14-15 . Accessed May 22, 2020</Citation></Reference><Reference><Citation>Benkirane R, Soulaymani Bencheikh R, Khattabi A, Benabdallah G, Alj L, Sefiani H, Hedna K, Ouammi L, Olsson S, Pal SN (2015) Assessment of a new instrument for detecting preventable adverse drug reactions. Drug Saf 38(4):383–393. https://doi.org/10.1007/s40264-014-0257-5</Citation><ArticleIdList><ArticleId IdType="doi">10.1007/s40264-014-0257-5</ArticleId><ArticleId IdType="pubmed">25537235</ArticleId></ArticleIdList></Reference><Reference><Citation>National Coordinating Council for Medication Error Reporting and Prevention. Taxonomy of medication errors. https://www.nccmerp.org/sites/default/files/taxonomy2001-07-31.pdf . Accessed 7 May 2020.</Citation></Reference><Reference><Citation>La Société Française de Pharmacie Clinique. Dictionnaire Français de l’Erreur Médicamenteuse. http://optimizsih-circ-med.fr/Documents/Dictionnaire_SFPC_EM.pdf . Accessed 7 May 2020.</Citation></Reference><Reference><Citation>World Health Organization. The World Health Organization Adverse Reaction Terminology. December 2005. http://www.pharmadhoc.com/uploads/3/2/7/4/3274790/who-art_2005.pdf . Accessed 3 June 2020.</Citation></Reference><Reference><Citation>International Conference on Harmonisation of Technical Requirements for registration of pharmaceuticals for human Use. ICH harmonised tripartite guideline. Note for guidance on definitions and standards for expedited reporting. ICH Topic E2D Post Approval Safety Data Management step 5. https://www.ema.europa.eu/en/documents/scientific-guideline/international-conference-harmonisation-technical-requirements-registration-pharmaceuticals-human-use_en-12.pdf (2004). Accessed 12 May 2020.</Citation></Reference><Reference><Citation>World Health organization. WHO Collaborating Centre for Drug Statistics Methodology, Guidelines for ATC classification and DDD assignment 2020. Oslo, Norway, 2019. https://www.whocc.no/filearchive/publications/2020_guidelines_web.pdf . Accessed 17 June 2020.</Citation></Reference><Reference><Citation>Council for International Organizations of Medical Sciences. Practical aspects of signal detection in pharmacovigilance. Working group VIII. https://cioms.ch/working_groups/working-group-viii/ (2010). Accessed 12 May 2020.</Citation></Reference><Reference><Citation>Massachusetts Medical Society. Patient safety curriculum: case studies and root cause analysis of adverse events. http://www.massmed.org/Advocacy/Key-Issues/Patient-Safety-Curriculum/#.Xt0yscDjLIU . Accessed 12 May 2020.</Citation></Reference><Reference><Citation>Newbould V, Le Meur S, Goedecke T, Kurz X (2017) Medication errors: a characterisation of spontaneously reported cases in EudraVigilance. Drug Saf 40:1241–1248</Citation><ArticleIdList><ArticleId IdType="doi">10.1007/s40264-017-0569-3</ArticleId></ArticleIdList></Reference><Reference><Citation>Salmasi S, Khan TM, Hong YH, Ming LC, Wong TW (2015) Medication errors in the Southeast Asian countries: a systematic review. PLoS ONE 10(9):e0136545. https://doi.org/10.1371/journal.pone.0136545</Citation><ArticleIdList><ArticleId IdType="doi">10.1371/journal.pone.0136545</ArticleId><ArticleId IdType="pubmed">26340679</ArticleId><ArticleId IdType="pmcid">4560405</ArticleId></ArticleIdList></Reference><Reference><Citation>Mansouri A, Ahmadvand A, Hadjibabaie M, Kargar M, Javadi M, Gholami K (2013) Types and severity of medication errors in Iran; a review of the current literature. Daru 21(1):49. https://doi.org/10.1186/2008-2231-21-49</Citation><ArticleIdList><ArticleId IdType="doi">10.1186/2008-2231-21-49</ArticleId><ArticleId IdType="pubmed">23787134</ArticleId><ArticleId IdType="pmcid">3694014</ArticleId></ArticleIdList></Reference><Reference><Citation>Alsulami Z, Conroy S, Choonara I (2013) Medication errors in the Middle East countries: a systematic review of the literature. Eur J Clin Pharmacol 69:995–1008</Citation><ArticleIdList><ArticleId IdType="doi">10.1007/s00228-012-1435-y</ArticleId></ArticleIdList></Reference><Reference><Citation>Tanti A, Camilleri M, Bonanno PV, Borg JJ (2013) Medication errors through a national pharmacovigilance database approach: a study for Malta. Int J Risk Saf Med 25:17–27. https://doi.org/10.3233/JRS-120582</Citation><ArticleIdList><ArticleId IdType="doi">10.3233/JRS-120582</ArticleId><ArticleId IdType="pubmed">23442294</ArticleId></ArticleIdList></Reference><Reference><Citation>Patel RR, Karelia BN (2018) Detecting medication errors from adverse drug reaction monitoring center database - a retrospective analysis. Int J Pharm Sci Res 9(6):2520–2524. https://doi.org/10.13040/IJPSR.0975-8232.9(6)0.2520-24</Citation><ArticleIdList><ArticleId IdType="doi">10.13040/IJPSR.0975-8232.9(6)0.2520-24</ArticleId></ArticleIdList></Reference><Reference><Citation>Abdullah Ghaleb M, Barber N, Franklin BD, Yeung VWS, Khaki ZF, Ian CK, Wong ICK (2006) Systematic review of medication errors in pediatric patients. Ann Pharmacother 40:1766–1776. https://doi.org/10.1345/aph.1G717</Citation><ArticleIdList><ArticleId IdType="doi">10.1345/aph.1G717</ArticleId></ArticleIdList></Reference><Reference><Citation>Miller MA (2001) Gender-based differences in the toxicity of pharmaceuticals-the Food and Drug Administration’s perspective. Int J Toxicol 20(3):149–152</Citation><ArticleIdList><ArticleId IdType="doi">10.1080/109158101317097728</ArticleId></ArticleIdList></Reference><Reference><Citation>Bates DW, Cullen DJ, Laird N, Petersen LA, Small SD, Servi D, Laffel G, Sweitzer BJ, Shea BF, Hallisey R (1995) Incidence of adverse drug events and potential adverse drug events: Implications for prevention. JAMA 274:29–34.9</Citation><ArticleIdList><ArticleId IdType="doi">10.1001/jama.1995.03530010043033</ArticleId></ArticleIdList></Reference><Reference><Citation>Leape LL, Bates DW, Cullen DJ, Cooper J, Demonaco HJ, Gallivan T, Hallisey R, Ives J, Laird N, Laffel G (1995) Systems analysis of adverse drug events. JAMA 274:35–43</Citation><ArticleIdList><ArticleId IdType="doi">10.1001/jama.1995.03530010049034</ArticleId></ArticleIdList></Reference><Reference><Citation>World Health Organization. WHO pharmacovigilance indicators: a practical manual for the assessment of pharmacovigilance systems. (2015). https://apps.who.int/iris/handle/10665/186642 . Accessed 3 June 2020.</Citation></Reference><Reference><Citation>Institute for Safe Medication Practices. Oral methotrexate. https://www.ismp.org/sites/default/files/attachments/2018-11/Methotrexatefinal.pdf . Accessed 17 October 2020.</Citation></Reference><Reference><Citation>Davanzo F, Settimi L, Giordano F, Casini ML, Ferrazin F (2015) Inadvertent oral administration of methylergometrine maleate to children in the first months of life: from surveillance to prevention. Pharmacoepidemiol Drug Saf 24(3):269–275. https://doi.org/10.1002/pds.3730</Citation><ArticleIdList><ArticleId IdType="doi">10.1002/pds.3730</ArticleId><ArticleId IdType="pubmed">25644278</ArticleId></ArticleIdList></Reference><Reference><Citation>Accidental child poisoning with methylergometrine intended for the mother. Prescrire Int. 2005;14(75):23-4.</Citation></Reference><Reference><Citation>Kaguelidou F, Beau-Salinas F, Jonville-Bera AP, Jacqz-Aigrain E (2016) Neonatal adverse drug reactions: an analysis of reports to the French pharmacovigilance database. Br J Clin Pharmacol 82(4):1058–1068. https://doi.org/10.1111/bcp.13034</Citation><ArticleIdList><ArticleId IdType="doi">10.1111/bcp.13034</ArticleId><ArticleId IdType="pubmed">27276109</ArticleId><ArticleId IdType="pmcid">5137831</ArticleId></ArticleIdList></Reference><Reference><Citation>Rajanayagam J, Bishop JR, Lewindon PJ, Evans HM (2015) Paracetamol-associated acute liver failure in Australian and New Zealand children: high rate of medication errors. Arch Dis Child 100:77–80. https://doi.org/10.1136/archdischild-2013-304902</Citation><ArticleIdList><ArticleId IdType="doi">10.1136/archdischild-2013-304902</ArticleId><ArticleId IdType="pubmed">25228327</ArticleId></ArticleIdList></Reference><Reference><Citation>Medication Errors: Technical Series on Safer Primary Care. Geneva: World Health Organization;2016. https://apps.who.int/iris/bitstream/handle/10665/252274/9789241511643-eng.pdf;sequence=1 . Accessed 21 October 2020</Citation></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>Maroc</li><li>Suède</li></country><region><li>Rabat-Salé-Kénitra</li></region><settlement><li>Rabat</li></settlement></list><tree><country name="Maroc"><region name="Rabat-Salé-Kénitra"><name sortKey="Alj, Loubna" sort="Alj, Loubna" uniqKey="Alj L" first="Loubna" last="Alj">Loubna Alj</name></region><name sortKey="Alj, Loubna" sort="Alj, Loubna" uniqKey="Alj L" first="Loubna" last="Alj">Loubna Alj</name><name sortKey="Benabdallah, Ghita" sort="Benabdallah, Ghita" uniqKey="Benabdallah G" first="Ghita" last="Benabdallah">Ghita Benabdallah</name><name sortKey="Benkirane, Raja" sort="Benkirane, Raja" uniqKey="Benkirane R" first="Raja" last="Benkirane">Raja Benkirane</name><name sortKey="Khattabi, Asmae" sort="Khattabi, Asmae" uniqKey="Khattabi A" first="Asmae" last="Khattabi">Asmae Khattabi</name><name sortKey="Khattabi, Asmae" sort="Khattabi, Asmae" uniqKey="Khattabi A" first="Asmae" last="Khattabi">Asmae Khattabi</name><name sortKey="Soulaymani Bencheikh, Rachida" sort="Soulaymani Bencheikh, Rachida" uniqKey="Soulaymani Bencheikh R" first="Rachida" last="Soulaymani Bencheikh">Rachida Soulaymani Bencheikh</name><name sortKey="Tebaa, Amina" sort="Tebaa, Amina" uniqKey="Tebaa A" first="Amina" last="Tebaa">Amina Tebaa</name></country><country name="Suède"><noRegion><name sortKey="Zekaria, Alem" sort="Zekaria, Alem" uniqKey="Zekaria A" first="Alem" last="Zekaria">Alem Zekaria</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MaghrebDataLibMedV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000060 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000060 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MaghrebDataLibMedV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:33598764
|texte= Construction and analysis of a database for medication errors in a pharmacovigilance centre-the Moroccan experience.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:33598764" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a MaghrebDataLibMedV1
| This area was generated with Dilib version V0.6.38. |  |